افسردگی اساسی در بزرگسالی و ازدست دادن والدین پیش از 18 سالگی

 AbstractObjectives: The aim of this study was to assess the correlation of parental loss in childhood and adole- scence with major depressive disorder in adulthood. Method:This was a case-control and post hoc study of 64 patients diagnosed with major depressive disorder based on DSM-IV criteria.The control group was comprised of 68 patients,none diagnosed with depression. Both groups were selected from university hospitals of Tehran.Findings:19 patients in the case group (29.7%) had experienced the loss of at least one parent before the age of eighteen,whereas seven patients in the control group (10.3%) had the same experience. In another words,the prevalence of parental loss before the age of eighteen years old was significant- ly more in the group with the diagnosis of major depressive disorder than the control group (P<0.05). Results:There is a statistically significant correlation between parental loss in childhood and adole- scence with major depressive disorder in adulthood.